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In the kidney, we observed widespread disruption in energy metabolism and multiple molecules involved in glycolysis, gluconeogenesis, and the TCA cycle were depleted, indicating a more global disruption in energy metabolism than has been previously appreciated

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doi: 10.3390/ijms18050984 144

It also changed the structure of the cell membrane (SSC, side scatter) and cell size (FSC, forward scatter), increased the level of ROS and fluorescence of FITC conjugated with annexin V

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These FMN particles appeared to lower riboflavin kinase expression in the microglia, preventing TNFR1/NF-B signaling and pro-inflammatory cytokine release 71