Dysmenorrhea, painful intercourse, painful bowel movements, bloating (often called "endo belly"), fatigue, and depression and anxiety are all part of the picture
The primary objective was to compare tirzepatide with placebo in terms of the change in glycated hemoglobin (HbA1c) from baseline at 12 weeks
Rather than alterations in single components, the impact on depression pathobiology may be due to the net effect of different dysregulations and interrelated compensatory mechanisms in such a complex network, which could be fully unraveled only by further functional and mechanistic studies
This regulatory complexity can not only slow down market entry for new therapies but may also deter investment in innovative diabetes treatments
RELATED STORIES Like the new study, this previous work compared GLP-1 users with "women with similar BMI near the start of pregnancy but with no history of GLP-1RA use," the commentary authors added
provider determines eligibility