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It has been suggested that keratinocytes, through the release of biological mediators, proopiomelanocortin (POMC)-derived peptides, basic fibroblast growth factor, and endothelins, regulate proliferation and differentiation of melanocytes and stimulate melanogenesis through receptor-mediated signalling pathways [20]

Furthermore, subcutaneous injection results showed that sEV-semaglutide exhibited glucose-lowering effects similar to semaglutide (Figure 3C)

The answer is yes, dizziness is among the reported side effects of semaglutide, though its important to note that not everyone will experience this

In the STEP 1 trial, participants who reached and maintained this dose level showed meaningful weight loss over the study period

Functional enrichment analysis using the Gene Ontology (GO) database revealed significant associations with biological processes (BP), cellular components (CC), and molecular functions (MF), with particular enrichment in mitochondria-related functions among the top 20 correlations (Fig

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