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Weight loss itself can alter hormone levels and potentially trigger vasomotor symptoms independent of medication effects

Unfortunately, bodies aren't so simple, and when they need nutrients and energy, they'll pull it from anywhere they can

However, a more effective approach for weight loss and maintenance would involve strategies that both suppress appetite and promote energy expenditure

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Improvements in glycaemic control 6 months after treatment initiation were sustained at 12 months, whereas maximum weight loss benefits required at least 12 months to become apparent