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Perot, G

This type of medication behaves similarly to natural GLP-1 hormones in the body by promoting the production of insulin by the pancreas, supporting a sense of satiety while also slowing the movement of food along the digestive tract and by inhibiting the secretion of glucagon as food is digested

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Our patch-clamp electrophysiology results corroborate these findings, demonstrating that GLP-1RAs directly activate DMH GLP-1R neurons, which in turn send inhibitory projections to ARC AgRP/NPY neurons [69]