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In particular, LEAP2 (liver-expressed antimicrobial peptide 2), an endogenous antagonist of the ghrelin receptor GHSR, has emerged as a potential target for mitigating the weight regain often observed after discontinuation of GLP-1-based therapies [22,23]

IL-17 produced by T helper (Th) 17 cells upregulates RANKL expression, which is dependent on the IL-17/IL-17 receptor A (IL-17RA)/STAT-3 signaling cascade in FLS (81)

B12 is also a key player in energy metabolism, as it helps the body convert food into glucose, which is then used as fuel by the body

Estos resultados preliminares abren lneas de investigacin fascinantes, aunque an lejos de una aplicacin clnica