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Eating behaviorincluding meal timing, food reward, satiety responsiveness, and even mindful eatingcan impact the release and activity of GLP-1 (Huber et al 2024)

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The exception, Trefethen said, was in opioids, where the efficacy was more limited compared with other substances

Affordability and access While clinical innovation is expanding the potential GLP-1 patient base, with approvals over the last year also in cardiovascular and kidney disease and sleep apnea, the question of access remains deeply unresolved, especially in the US market

patients should be advised to use non-oral or additional contraceptive methods, especially during dose initiation and escalation

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