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Helps preserve lean muscle while promoting fat loss
For the B 12 bolus experiment, mice were administered 5 g vitamin B 12 (Sigma, V2876) dissolved in water by oral gavage on day 6 after the start of doxycycline treatment, and blood samples were taken by submandibular collection just before and 24 h after the bolus
Rotating injection sites prevents chronic irritation
Oral B12 (50150 g daily) may be appropriate for dietary deficiency without neurological involvement, but intramuscular hydroxocobalamin injections remain first-line treatment in the UK for patients with nerve symptoms or malabsorption conditions
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