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By Brooke Hudspeth University of Kentucky Most people have likely heard about the new weight-loss and diabetes management drugs called Ozempic and Mounjaro, which are also called GLP-1 medications, short for glucagon-like peptide-1 agonists, but they may not have heard about their side effects

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It refers to retatrutide, a tripleagonist weightloss medication that activates GLP1, GIP, and glucagon receptors. Early clinical trials show unprecedented weightloss results, often greater than currently approved GLP1 and dualagonist drugs, along with improvements in liver fat and metabolic markers. As research advances and more data become available, medically supervised programs will continue to evaluate where TRIPLEagonist medications fit among GLP1 drugs, dualagonists, peptides, and other tools for sustainable metabolic health

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Once opened, most compounded sublingual formulations remain stable for 28 to 90 days in the refrigerator, depending on the pharmacy and formulation