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New England Journal of Medicine, 2023

By addressing obesity and metabolic dysfunction, GLP-1s indirectly help restore testosterone balance in men with weight-related hormonal issues

Oct 31 2020;21(21)doi:10.3390/ijms21218178 Lau E, Belda E, Picq P, et al

Biometals 39 , 809837 (2026)

That is where phase III comes in moving the phase II conjugated metabolites across cell membranes and out toward the bile or urine

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