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Multiple clinical guidelines now recommend these therapies for patients with type 2 diabetes at high cardiorenal risk, regardless of blood sugar levels

This can include: Frequent thoughts about specific foods, particularly those high in sugar or fat Difficulty feeling satisfied after meals, leading to continued eating Planning meals or snacks excessively throughout the day Emotional distress when food is unavailable or restricted The impact on eating behaviour can be substantial

Semaglutide is a GLP-1 receptor agonist, which means it mimics the action of the glucagon-like peptide-1 hormone in the body

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This creates an extraordinarily high binding affinity with pK = 16.44, approximately 10 million times higher than other tripeptides and comparable to albumins copper binding (pK = 16.2)