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Vitamin B12 is a co-factor in the transfer of methyl groups in the body, important in the synthesis of DNA

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Specifically, IL-2, IFN-, TNF, PFP and Gzms-B increased by 76%, 33%, 29%, 73% and 58%, respectively, in the combination group, versus 41%, 18%, 17%, 49% and 35% in the monotherapy group (Supplementary Fig

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The three major routes of administration used for skin lightening are topical (creams, face washes), oral (capsules and sublingual/buccal tablets) and intravenous injections

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