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clinician determines final eligibility Who shouldn't apply: Personal or family history of medullary thyroid carcinoma or MEN 2 syndrome, history of pancreatitis, certain severe GI or kidney conditions, pregnancy, or breastfeeding - clinician screens at intake FDA regulatory status as of June 2026: Active enforcement and regulatory change ongoing

However, this process still faces several technical bottlenecks, mechanistic controversies, and challenges related to therapeutic adaptability

Unlike intravenous administration, subcutaneous injections deliver medication into fatty tissue where any small air bubble is absorbed harmlessly by surrounding tissue

Therefore, an innovative dosage form needed to be tested