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Potential benefits of MOTS-c: Improved insulin sensitivity Better glucose control Increased exercise capacity Enhanced mitochondrial function Improved metabolic flexibility Unlike Semaglutide or Tirzepatide, MOTS-c does not primarily work by reducing appetite

It targets hormones GLP-1 and GIP to control appetite, leading to significant weight loss

Strategies that reduce GI side effects: Taking the weekly injection in the evening so peak nausea occurs during sleep Eating smaller, lower-fat meals during the titration period Avoiding high-fat, fried, or heavily seasoned foods which worsen nausea Maintaining consistent hydration to prevent compounding issues Women experience more nausea than men Clinical trial data shows that nausea and vomiting are reported at higher rates in women than men on semaglutide

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Bruls YMH, Kamp YJM, op den, Phielix E, Lindeboom L, Havekes B, Schaart G, et al

Take Our Quiz What You Need to Know About GLP-1s and Hormone Therapy for Menopause Belly Fat If you're in perimenopause or menopause, you've likely noticed your body shifting in ways that feel out of your control