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79 This upregulation correlates with obesity severity, adipocyte hypertrophy, and adverse glucometabolic status, reflecting a tightly regulated interplay between autophagy, tissue remodeling, and metabolic stress

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GIP receptor activation at low doses supports mitochondrial function in adipose tissue and may contribute to improved fatty acid metabolism independent of the dramatic appetite suppression seen at full doses

6 Wang H, Liu Y, Chen Z, Sun L, Zhao Y

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