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Share: Patients prescribed drugs to help them lose weight may experience a rebound in weight gain after halting their prescription, finds a meta-analysis published in BMC Medicine

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During weight loss and metabolic shiftcommon experiences in GLP-1 therapycells may experience transient oxidative stress as energy metabolism increases and adipose tissue remodeling occurs

Why commercial patches cant deliver GLP-1 effects There are three key scientific reasons why current commercial patches cannot deliver GLP-1-like effects: 1

Zabezhinski (2002) Inhibitory effect of peptide Epitalon on colon carcinogenesis induced by 1,2-dimethylhydrazine in rats Cancer Letters, Volume 183, Issue 1, 8 September 2002, Pages 1-8

Results We included 1,647,238 patients who were prescribed a GLP-1 RA between January 2024 and July 2025, with 6,059,445 total GLP-1 RA prescriptions during this period