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Percent change in weight from baseline and proportion of patients achieving a weight loss of 5% were the co-primary endpoints

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In the STEP 1 extension, people who stopped semaglutide regained 11.6 percentage points of body weight over 52 weeks, ending with an average net loss of 5.6% from baseline while lifestyle support continued (STEP 1 extension data)

These dual actions on blood vessels and immune responses underpin many of the peptides proposed healing advantages

(2017b)

If youre considering a compounded medication, understand that compounded drugs are not FDA-approved, have not been reviewed by the FDA for safety or efficacy, and may vary in formulation or potency