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27 Our study revealed that some mild adverse events occurred in the first four weeks, although this occurrence was not statistically significant

Moiz, A., Filion, K

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Autonomic disturbances can also occur between episodes, such as reflex sympathetic dystrophy (a chronic pain condition), syncope/POTS (fainting) and disorders of gastrointestinal motility

Side effects are rare typically mild redness at the application site

Following intra-articular (LEGEND Injectable Solution 2 mL only) use: lameness, joint effusion, joint or injection site swelling and joint pain