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Before any medication change, confirm the product status, the source, the clinical reason for combining therapies, and the plan for monitoring side effects

You should go to the ER immediately if you experience severe headaches, confusion, black or tarry stools, vomiting blood, or any bleeding you cannot control

With regard to substitution in cases of existing B12 deficiency, the fact that B12 sensitisation is mainly triggered by injections makes it advisable to avoid intramuscular administration

The NHS recommends that adults require approximately 1.5 micrograms of vitamin B12 daily, a target readily achievable through a balanced diet for most people

Semaglutide side effects are transient and time-limited, with most gastrointestinal symptoms being short-lived