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These medications also support weight reduction and may offer cardiovascular protection depending on the agent and patient profile

Antioxidants 9(12):1227

Clinical studies show long-term safety and benefits for weight and cardiometabolic health when medically supervised

This led to clinical trials specifically for obesity, and several are now FDA-approved for weight management

Theres probably 50 years of research, and theyve been available for 20 years longer than most people realize, says Rekha Kumar, MD, an endocrinologist and obesity medicine expert at Weill Cornell Medical College and NewYork-Presbyterian Hospital in New York City

The combined appetite suppression may lead to insufficient caloric or nutritional intake, particularly in patients who are not overweight or who lose weight rapidly