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Patients with certain FTO and MC4R variants may experience accelerated improvements in liver fat content when taking semaglutide, while those with specific GLP1R polymorphisms might benefit from dose optimization to achieve therapeutic GLP-1 receptor saturation

Related reading: More Than a Number: Bariatric Surgery, GLP-1 Medications and Tools to Treat Obesity

It can still work, but the progress might be slower and harder to maintain

That's not a brand claim

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It contains semaglutide, which is the active ingredient