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As a putative bridge between carnitine and S-5-HT, increased energy production allowed by L-carnitine supplementation might promote peripheral 5-HT synthesis
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The use of the Ca 2+ -sensitive receptor (CaSR) inhibitor NPS-2143 can block the carnitine-induced increase in the cytoplasmic Ca 2+ concentration, indicating that carnitine-induced Ca 2+ mobilization is mediated by the activation of CaSR [119]
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Third, we did not investigate the cell cycle or apoptosis in the oxidative stress-induced senescence model
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